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NOD1 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP03837-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03837-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD)| a centrally located nucleotide-binding domain (NBD)| and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling| LRRs participate in protein-protein interactions| and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described| but the full-length nature of these variants has not been determined.
CAS Number
9007-83-4
Synonyms
NOD1; Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human NOD1
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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