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NEDD4L Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP11514-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP11514-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates| thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel| ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
CAS Number
9007-83-4
Synonyms
NEDD4L; E3 ubiquitin-protein ligase NEDD4-like; EC 6.3.2.-; NEDD4.2; Nedd4-2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human NEDD4L
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG