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NCF1C Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP03775-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03775-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase| which produces superoxide anion. The NCF1 gene is located in close proximity to two highly similar| multi-exon pseudogenes at chromosome 7q11.23| corresponding to this gene record and GeneID:654816. The two pseudogenes contain a dinucleotide deletion (delta-GT) in exon 2 that results in a frameshift and truncation of the open reading frame| and neither pseudogene is likely to express a protein. Recombination events between the pseudogenes and the functional NCF1 gene can inactivate the NCF1 gene and result in chronic granulomatous disease.
CAS Number
9007-83-4
Synonyms
NCF1C
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human NCF1C
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
40260
Antibody Type
Primary antibody
Isotype
IgG