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MPZL2 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP11359-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP11359-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and| in thymus-derived epithelial cell lines| is poorly soluble in nonionic detergents| strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene.
CAS Number
9007-83-4
Synonyms
MPZL2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human MPZL2
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
23650
Antibody Type
Primary antibody
Isotype
IgG

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