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LFTY2 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP03403-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03403-01Size:20 µL
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Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein| which plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations| particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. This gene is closely linked to both a related family member and a related pseudogene. This gene encodes multiple isoforms that may undergo similar proteolytic processing.
CAS Number
9007-83-4
Synonyms
LFTY2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human LFTY2
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
40260
Antibody Type
Primary antibody
Isotype
IgG