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GEN Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP10142-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP10142-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family| whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions| which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition| this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
GEN
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human GEN
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
99880
Antibody Type
Primary antibody
Isotype
IgG