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FBX22 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP02646-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02646-01Size:20 µL
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Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and| as a transcriptional target of the tumor protein p53| is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
FBX22
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human FBX22
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
44330
Antibody Type
Primary antibody
Isotype
IgG