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FACR1 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP02620-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02620-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols| a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction| and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein| and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome| while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability| early-onset epilepsy| microcephaly| congenital cataracts| growth retardation| and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13.
CAS Number
9007-83-4
Synonyms
FACR1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human FACR1
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
56650
Antibody Type
Primary antibody
Isotype
IgG

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