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FA11 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP09942-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09942-01Size:20 µL
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Background
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.
CAS Number
9007-83-4
Synonyms
FA11
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human FA11
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
68750
Antibody Type
Primary antibody
Isotype
IgG