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DUOX1 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP02326-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02326-01Size:20 µL
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Background
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter| thyroperoxidase| and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase| lactoperoxidase| and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
CAS Number
9007-83-4
Synonyms
DUOX1
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from human DUOX1
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
170610
Antibody Type
Primary antibody
Isotype
IgG