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DSE Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP09343-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09343-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9| and a paralogous gene exists on chromosome 18.
CAS Number
9007-83-4
Synonyms
DSE; Dermatan-sulfate epimerase; DS epimerase; EC 5.1.3.19; Chondroitin-glucuronate 5-epimerase; Squamous cell carcinoma antigen recognized by T-cells 2; SART-2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human DSE
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG