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DAZL Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP02130-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02130-01Size:20 µL
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Background
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis| this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
DAZL
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human DAZL
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
32450
Antibody Type
Primary antibody
Isotype
IgG