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CEL3B Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP07503-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07503-01Size:20 µL
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Background
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1| 2| 2A| 2B| 3A| and 3B. Unlike other elastases| elastase 3B has little elastolytic activity. Like most of the human elastases| elastase 3B is secreted from the pancreas as a zymogen and| like other serine proteases such as trypsin| chymotrypsin and kallikrein| it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1| and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
CAS Number
9007-83-4
Synonyms
CEL3B
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human CEL3B
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
29700
Antibody Type
Primary antibody
Isotype
IgG