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CACNA1C Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP06772-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06772-01Size:20 µL
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Background
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1| alpha-2/delta| beta| and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins| either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.
CAS Number
9007-83-4
Synonyms
CACNA1C; Voltage-dependent L-type calcium channel subunit alpha-1C; Calcium channel; L type; alpha-1 polypeptide; isoform 1; cardiac muscle; Voltage-gated calcium channel subunit alpha Cav1.2
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human CACNA1C
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
244310
Antibody Type
Primary antibody
Isotype
IgG