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ANO3 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP00426-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00426-01Size:20 µL
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Background
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins| that are also known as anoctamins. While little is known about the function of this gene| mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with| and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Synonyms
ANO3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human ANO3
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
107910
Antibody Type
Primary antibody
Isotype
IgG