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CENP-M Polyclonal Antibody

CAT: 0965-JOT-AP01502-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01502-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is an inner protein of the kinetochore| the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group| whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein| CENP-I| impairs kinetochore assembly and chromosome alignment| suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
CENP-M; Centromere protein M; CENP-M; Interphase centromere complex protein 39; Proliferation-associated nuclear element protein 1
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human CENP-M
Clonality
Polyclonal
Applications
IHC-p, IF, WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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