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VRK3 Polyclonal Antibody

CAT: 0965-JOT-AP09557-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09557-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VRK3 (vaccinia related kinase 3) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, VRK3 has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.
CAS Number
9007-83-4
Synonyms
VRK3; Inactive serine/threonine-protein kinase VRK3; Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human VRK3.
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
52881
Antibody Type
Primary antibody
Isotype
IgG