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Tyk 2 Polyclonal Antibody

CAT: 0965-JOT-AP09318-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09318-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
CAS Number
9007-83-4
Synonyms
TYK2; Non-receptor tyrosine-protein kinase TYK2
Host
Rabbit
Reactivity
Human;Mouse;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human TYK2. AA range:1020-1069
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
133650
Antibody Type
Primary antibody
Isotype
IgG

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