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Trk A Polyclonal Antibody

CAT: 0965-JOT-AP09211-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09211-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NTRK1 encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
CAS Number
9007-83-4
Synonyms
NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinas
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Trk A. AA range:471-520
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
87497
Antibody Type
Primary antibody
Isotype
IgG