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TRAF1 Polyclonal Antibody

CAT: 0965-JOT-AP09167-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09167-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by TRAF1 (TNF receptor associated factor 1) is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for TRAF1.
CAS Number
9007-83-4
Synonyms
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
Synthesized peptide derived from TRAF1 at AA range: 191-240
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
46164
Antibody Type
Primary antibody
Isotype
IgG

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