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TMEM173 Polyclonal Antibody

CAT: 0965-JOT-AP09082-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09082-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TMEM173 encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The transmembrane protein 173 is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
TMEM173; ERIS; MITA; STING; Transmembrane protein 173; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Stimulator of interferon genes protein; hSTING
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
Synthesized peptide derived from Transmembrane protein 173 at AA range: 301-350
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
42193
Antibody Type
Primary antibody
Isotype
IgG

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