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TIRAP Polyclonal Antibody

CAT: 0965-JOT-AP09046-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09046-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The TIR domain containing adaptor protein encoded by TIRAP is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
CAS Number
9007-83-4
Synonyms
TIRAP; MAL; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TIRAP. AA range:52-101
Clonality
Polyclonal
Applications
IHC-p, WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
23883
Antibody Type
Primary antibody
Isotype
IgG

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