Products for Research Use Only
RegisterLogin

THP Polyclonal Antibody

CAT: 0965-JOT-AP09001-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP09001-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by UMOD (uromodulin) is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in UMOD are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of UMOD results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
UMOD; Uromodulin; Tamm-Horsfall urinary glycoprotein; THP
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human THP. AA range:329-378
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
69761
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-EK4743Hu-01Human Uromodulin,THP;UMOD ELISA KIT
JOT-EK1968Hu-01Human T-H glycoprotein,THP ELISA KIT
JOT-AP01329-01CD10 Polyclonal Antibody
JOT-AP01765-01Chk1 Polyclonal Antibody
JOT-AP01456-01CD300d Polyclonal Antibody
JOT-AP02080-01COL2A1 Polyclonal Antibody
JOT-AP01580-01Cdc25B Polyclonal Antibody
JOT-AP01332-01CD101 Polyclonal Antibody
JOT-AP01505-01CD44 Polyclonal Antibody
JOT-AP01469-01CD31 Polyclonal Antibody

Alternative Products

CatalogName
APR00460GPolyclonal Spt16 polyclonal antibody
APG01659GPolyclonal AKR1B10 Polyclonal Antibody
APR11188GPolyclonal Rtf1 polyclonal antibody
AMR09486GPolyclonal PPARG polyclonal antibody
APR13475GPolyclonal SOX4 polyclonal antibody
APR00375GPolyclonal JMJD2c polyclonal antibody
APR00449GPolyclonal Hira polyclonal antibody
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody

Popular Products