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SR-1F Polyclonal Antibody

CAT: 0965-JOT-AP08532-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08532-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HTR1F (5-Hydroxytryptamine Receptor 1F) is a Protein Coding gene. Diseases associated with HTR1F include migraine with or without aura 1. Among its related pathways are Signaling by GPCR and cAMP signaling pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and serotonin binding. An important paralog of this gene is DRD4. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Serotonin 5-HT1F receptors, previously known as 5-HT1Ebeta receptors, are located primarily in the hippocampus, cortex and dorsal raphe nucleus. The human 5-HT1F receptor is closely related to the 5-ht1E receptor and its gene has been localized to chromosome 3 (3q11).
CAS Number
9007-83-4
Synonyms
HTR1F; HTR1EL; 5-hydroxytryptamine receptor 1F; 5-HT-1F; 5-HT1F; Serotonin receptor 1F
Host
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human 5-HT-1F. AA range:101-150
Clonality
Polyclonal
Applications
WB, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
41709
Antibody Type
Primary antibody
Isotype
IgG

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