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SERCA2 Polyclonal Antibody

CAT: 0965-JOT-AP08226-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08226-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ATP2A2 encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Synonyms
ATP2A2; ATP2B; Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca(2+)-ATPase 2; Calcium pump 2; Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle iso
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human ATP2A2. AA range:841-890
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
114757
Antibody Type
Primary antibody
Isotype
IgG

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