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Sclerostin Polyclonal Antibody

CAT: 0965-JOT-AP08158-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08158-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sclerostin (SOST) is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in SOST are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
CAS Number
9007-83-4
Synonyms
SOST; Sclerostin
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from Sclerostin . at AA range: 130-210
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
24031
Antibody Type
Primary antibody
Isotype
IgG

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