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Rpb1 Polyclonal Antibody

CAT: 0965-JOT-AP07994-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07994-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
POLR2A encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
CAS Number
9007-83-4
Synonyms
POLR2A; POLR2; DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA po
Host
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human POLR2A. AA range:1585-1634
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
217206
Antibody Type
Primary antibody
Isotype
IgG