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ROM-K Polyclonal Antibody

CAT: 0965-JOT-AP07972-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07972-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by KCNJ1 is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
KCNJ1; ROMK1; ATP-sensitive inward rectifier potassium channel 1; ATP-regulated potassium channel ROM-K; Inward rectifier K(+) channel Kir1.1; Potassium channel; inwardly rectifying subfamily J membe
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ROMK/Kir1.1. AA range:11-60
Clonality
Polyclonal
Applications
IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
44795
Antibody Type
Primary antibody
Isotype
IgG

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