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Renin Polyclonal Antibody

CAT: 0965-JOT-AP07749-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07749-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in REN (renin) have been shown to cause familial hyperproreninemia.
CAS Number
9007-83-4
Synonyms
REN; Renin; Angiotensinogenase
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human REN. AA range:207-256
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
45057
Antibody Type
Primary antibody
Isotype
IgG

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