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Prothrombin Polyclonal Antibody

CAT: 0965-JOT-AP07415-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07415-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E.coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
F2; Prothrombin; Coagulation factor II
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized peptide derived from the Internal region of human Prothrombin.
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
70037
Antibody Type
Primary antibody
Isotype
IgG