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PDGFR- Alpha Polyclonal Antibody

CAT: 0965-JOT-AP07019-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07019-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PDGFRA encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
CAS Number
9007-83-4
Synonyms
PDGFRA; PDGFR2; RHEPDGFRA; Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor;C
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PDGFRA. AA range:351-400
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
122670
Antibody Type
Primary antibody
Isotype
IgG