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OPG Polyclonal Antibody

CAT: 0965-JOT-AP06576-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06576-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TNF receptor superfamily member 11b encoded by TNFRSF11B is a member of the TNF-receptor superfamily. TNF receptor superfamily member 11b is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. TNF receptor superfamily member 11b specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that TNF receptor superfamily member 11b and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of TNFRSF11B have been reported, but their full length nature has not been determined.
CAS Number
9007-83-4
Synonyms
TNFRSF11B; OCIF; OPG; Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TR11B . AA range:10-59
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
46040
Antibody Type
Primary antibody
Isotype
IgG