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MYBPC3 Polyclonal Antibody

CAT: 0965-JOT-AP05676-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05676-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
CAS Number
9007-83-4
Synonyms
MYBPC3; Myosin-binding protein C; cardiac-type; Cardiac MyBP-C; C-protein, cardiac muscle isoform
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human MYBPC3. AA range:329-378
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
140606
Antibody Type
Primary antibody
Isotype
IgG