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MSH3 Polyclonal Antibody

CAT: 0965-JOT-AP05623-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05623-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DNA mismatch repair protein Msh3 encoded by MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
CAS Number
9007-83-4
Synonyms
MSH3; DUC1; DUG; DNA mismatch repair protein Msh3; hMSH3; Divergent upstream protein; DUP; Mismatch repair protein 1; MRP1
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human MSH3. AA range:51-100
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
127456
Antibody Type
Primary antibody
Isotype
IgG

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