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MMP-1 Polyclonal Antibody

CAT: 0965-JOT-AP05470-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05470-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MMP1 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease (matrix metallopeptidase 1) breaks down the interstitial collagens, including types I, II, and III. MMP1 is part of a cluster of MMP genes on chromosome 11. Mutations in MMP1 are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
CAS Number
9007-83-4
Synonyms
MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from MMP-1 . at AA range: 190-270
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
54007
Antibody Type
Primary antibody
Isotype
IgG

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