Products for Research Use Only
RegisterLogin

MKP-4 Polyclonal Antibody

CAT: 0965-JOT-AP05445-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP05445-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The dual specificity phosphatase 9 encoded by DUSP9 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
DUSP9; MKP4; Dual specificity protein phosphatase 9; Mitogen-activated protein kinase phosphatase 4; MAP kinase phosphatase 4; MKP-4
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human DUSP9. AA range:151-200
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
41868
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP05447-01MKP-7 Polyclonal Antibody
JOT-AP05443-01MKP-2 Polyclonal Antibody
JOT-AP05444-01MKP-3 Polyclonal Antibody
JOT-AP05441-01MKP-1 Polyclonal Antibody
JOT-AP05446-01MKP-5 Polyclonal Antibody
JOT-AP05442-01MKP-1/2 Polyclonal Antibody
JOT-AP11356-01MKP-1(Phospho Ser359) Polyclonal Antibody
JOT-AP11358-01MKP-1/2(Phospho Ser296/318) Polyclonal Antibody
JOT-AP01824-01CKR-4 Polyclonal Antibody
JOT-AP02124-01Contactin 4 Polyclonal Antibody

Alternative Products

CatalogName
UB-GEN-14615MKP-4 Polyclonal Antibody
BS2348-01MKP-4 (A174) polyclonal antibody
APRab13935-01MKP-4 Rabbit Polyclonal Antibody
WP13181-01U-Blot® MKP-4 Polyclonal Antibody
GTR17694001MKP-1/DUSP1/MKP Rabbit Polyclonal Antibody
PA87555HU-01Rabbit Anti-Human MKP-4 Polyclonal Antibody
PAV8944Rabbit Anti-MKP-4/DUSP9 Polyclonal Antibody
GTR18551200MKP-1/DUSP1/MKP Rabbit Polyclonal Antibody (Biotin)
GTR18551199MKP-1/DUSP1/MKP Rabbit Polyclonal Antibody (Cy3)
GTR18551196MKP-1/DUSP1/MKP Rabbit Polyclonal Antibody (APC)

Popular Products