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MCT8 Polyclonal Antibody

CAT: 0965-JOT-AP05292-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05292-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SLC16A2 (solute carrier family 16 member 2) encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). SLC16A2 is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in SLC16A2 are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. SLC16A2 is subject to X-chromosome inactivation. Mutations in SLC16A2 are the cause of Allan-Herndon-Dudley syndrome.
CAS Number
9007-83-4
Synonyms
SLC16A2; MCT8; XPCT; Monocarboxylate transporter 8; MCT 8; Monocarboxylate transporter 7; MCT 7; Solute carrier family 16 member 2; X-linked PEST-containing transporter
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC16A2. AA range:112-161
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
59511
Antibody Type
Primary antibody
Isotype
IgG