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MARCH1 Polyclonal Antibody

CAT: 0965-JOT-AP05213-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05213-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MARCH1 (membrane associated ring-CH-type finger 1) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment.
CAS Number
9007-83-4
Synonyms
MARCH1; RNF171; E3 ubiquitin-protein ligase MARCH1; Membrane-associated RING finger protein 1; Membrane-associated RING-CH protein I; MARCH-I; RING finger protein 171
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human 40603.
Clonality
Polyclonal
Applications
IHC-p, WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
32308
Antibody Type
Primary antibody
Isotype
IgG

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