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LIFR Polyclonal Antibody

CAT: 0965-JOT-AP05011-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05011-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LIFR encodes leukemia inhibitory factor receptor alpha that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.
CAS Number
9007-83-4
Synonyms
LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human LIFR. AA range:731-780
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
123743
Antibody Type
Primary antibody
Isotype
IgG

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