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Jun B Polyclonal Antibody

CAT: 0965-JOT-AP04714-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04714-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice. JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML).
CAS Number
9007-83-4
Synonyms
JUNB; Transcription factor jun-B
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human JunB. AA range:46-95
Clonality
Polyclonal
Applications
WB, IHC-p, IP, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
35879
Antibody Type
Primary antibody
Isotype
IgG

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