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Integrin Alpha6 Polyclonal Antibody

CAT: 0965-JOT-AP04576-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04576-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ITGA6 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA6. AA range:901-950
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
126619
Antibody Type
Primary antibody
Isotype
IgG

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