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IL-1Beta Polyclonal Antibody

CAT: 0965-JOT-AP04469-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04469-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-1 beta encoded by IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
CAS Number
9007-83-4
Synonyms
IL1B; IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IL1B. AA range:181-230
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
30748
Antibody Type
Primary antibody
Isotype
IgG