HP1 Gamma Polyclonal Antibody

CAT: 0965-JOT-AP04201-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0965-JOT-AP04201-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The chromobox 3 encoded by CBX3 binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

CAS Number

9007-83-4

Synonyms

CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein

Host

Rabbit

Reactivity

Human;Mouse;Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human HP1 gamma. AA range:59-108

Clonality

Polyclonal

Applications

WB, IHC-p, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

20811

Antibody Type

Primary antibody

Isotype

IgG

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