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HDAC4 Polyclonal Antibody

CAT: 0965-JOT-AP03923-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03923-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. Histone deacetylase 4 does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
CAS Number
9007-83-4
Synonyms
HDAC4; KIAA0288; Histone deacetylase 4; HD4
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human HDAC4. AA range:598-647
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
119070
Antibody Type
Primary antibody
Isotype
IgG

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