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GHR Polyclonal Antibody

CAT: 0965-JOT-AP03560-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03560-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.
CAS Number
9007-83-4
Synonyms
GHR; Growth hormone receptor; GH receptor; Somatotropin receptor
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human GHR. AA range:21-70
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
71500
Antibody Type
Primary antibody
Isotype
IgG

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