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eIF4E Polyclonal Antibody

CAT: 0965-JOT-AP02898-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02898-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Eukaryotic translation initiation factor 4E encoded by EIF4E is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. EIF4E acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of EIF4E are found on other chromosomes. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
Host
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF4E. AA range:168-217
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
25097
Antibody Type
Primary antibody
Isotype
IgG

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