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dTMP Kinase Polyclonal Antibody

CAT: 0965-JOT-AP02747-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02747-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
CAS Number
9007-83-4
Synonyms
DTYMK; CDC8; TMPK; TYMK; Thymidylate kinase; dTMP kinase
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human DTYMK. AA range:1-50
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
23819
Antibody Type
Primary antibody
Isotype
IgG