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DOCK 2 Polyclonal Antibody

CAT: 0965-JOT-AP02693-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02693-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection.
CAS Number
9007-83-4
Synonyms
DOCK2; KIAA0209; Dedicator of cytokinesis protein 2
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized peptide derived from the Internal region of human DOCK 2.
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
211948
Antibody Type
Primary antibody
Isotype
IgG