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Cystatin E/M Polyclonal Antibody

CAT: 0965-JOT-AP02448-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02448-01Size:20 µL
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Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
CAS Number
9007-83-4
Synonyms
CST6; Cystatin-M; Cystatin-6; Cystatin-E
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human Cystatin E/M.
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
16511
Antibody Type
Primary antibody
Isotype
IgG

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