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c-Rel Polyclonal Antibody

CAT: 0965-JOT-AP02220-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02220-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
REL (REL proto-oncogene, NF-kB subunit) encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of REL is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in REL are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Synonyms
REL; Proto-oncogene c-Rel
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Rel. AA range:470-519
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
68520
Antibody Type
Primary antibody
Isotype
IgG

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